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tamoxifen or raloxifen?

carolyn cook Profile
Asked by

anonymous

Learning About Breast Cancer over 5 years
 
  • Sharon Danielson Profile
    anonymous
    Survivor since 2007
    Depends on YOU and how you tolerate either.
    over 5 years Comment Flag
  • Lou Cam Profile
    anonymous
    Survivor since 2013
    Carolyn, I'm all for raloxifen because it has less side effects, and does not have the drug interactions that tamoxifen does. The patient information that comes with it says that it has not been fully studied in women who have breast cancer. I think that is why it has not been FDA approved for the treatment of breast cancer - not because it is not effective - but because it has not been fully studied in women with breast cancer. It is approved for osteoporosis and for women at high risk of getting breast cancer. " Raloxifene has never been approved for use as a drug to treat bc. Sometimes it is offered to women who cannot tolerate the side effects of tamoxifen, but this is not done routinely". The study that has been done on r and t is the STAR study. It has studied the reduction of risk to women at high risk of getting bc. But not as a treatment for women with bc. Long term results have shown both to be effective : t reduces risk in high risk women by 50% , while r reduces by 38% . Updated results do show both effective for invasive and noninvasive.
    over 5 years Comment Flag
  • Lou Cam Profile
    anonymous
    Survivor since 2013
    My oncologist said that raloxifen is not approved for women with breast cancer. I asked. So, I looked it up. They are similar for reducing IDC, but raloxifen is not effective at reducing DCIS. Since DCIS can become invasive, tamoxifen is the more effective medicine. Raloxifen is sometimes given if tamoxifen cannot be given to tolerated. Both are good for your bones.
    over 5 years Flag
    • carolyn cook Profile
      anonymous
      Learning About Breast Cancer

      Interesting. I know that Raloxifen is recommended for bone loss, but also used for treating and preventing DCIS. my doctor gave me info on both. Still doing radiation, but will make a decision later this month. I saw that the effectiveness rate...

      more

      Interesting. I know that Raloxifen is recommended for bone loss, but also used for treating and preventing DCIS. my doctor gave me info on both. Still doing radiation, but will make a decision later this month. I saw that the effectiveness rate was very similar between tamoxifen and raloxifen. I didn't see that tamoxifen was good for bone loss.

      over 5 years Flag
    • Lou Cam Profile
      anonymous
      Survivor since 2013

      " Tomoxifen helps stop bone loss after menopause and lowers cholesterol levels. SERM : blocks estrogen's actions on breast cells, activates estrogen's action in bone and liver cells ".

      over 5 years Flag
  • Betti A Profile
    anonymous
    Survivor since 2013
    What is your doctor recommending? I know my onc. told me there were 2 different ones she could put me on and they both were about the same so she wrote a 'script for the one and said if it causes any problems or doesn't work we can try the other one. Everyone tolerates meds. differently.
    over 5 years Flag
    • Betti A Profile
      anonymous
      Survivor since 2013

      I got thinking, I have a friend who takes Raloxifene for her Osteoporosis, she doesn't have breast cancer.

      over 5 years Flag
    • carolyn cook Profile
      anonymous
      Learning About Breast Cancer

      yes, raloxifen was actually designed for bone loss, but found to be almost as effective in treating DCIS as tamoxifen. Recent trials show even closer rates of success. Just wondering about side effects on each one.

      over 5 years Flag
  • anonymous Profile
    anonymous
    Survivor since 2013
    Been on tamoxifen over 1 yr now and doing okay
    over 5 years Flag
    • carolyn cook Profile
      anonymous
      Learning About Breast Cancer

      have you had side effects?

      over 5 years Flag
    • anonymous Profile
      anonymous
      Survivor since 2013

      In the begininng gained a few lbs but was able to lose with diet and exercise. Nothing major like a expected a few hot flashes and aches and pains but hey at 57 yr what do you expect. Body seems to get used to after a few months. Overall doing ok...

      more

      In the begininng gained a few lbs but was able to lose with diet and exercise. Nothing major like a expected a few hot flashes and aches and pains but hey at 57 yr what do you expect. Body seems to get used to after a few months. Overall doing ok but might have to change to a post menopausal drug, however doc tells me I can go back to tamoxifen if we have to.

      over 5 years Flag
  • heather andreini Profile
    anonymous
    Learning About Breast Cancer
    I'm on tamoxifen, started a month ago and haven't had any side effects.
    over 5 years Comment Flag
  • Thumb avatar default
    anonymous
    Learning About Breast Cancer
    I was on tamoxifen for 2 years with no side effects.
    over 5 years Comment Flag

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