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Types & Stages

 
Types & Stages

Chapter: 5 - Types & Stages

Subchapter: 6 - Triple Negative Breast Cancer

In Subchapter 3.1, “Growth of Cancer”, we discussed the role of receptors in cancer cells. Doctors seek to determine what causes certain types of cancer to progress by identifying its “receptors”. These receptors function like mouths: when open, the cancer cells feed and rapidly grow.

Triple Negative Breast Cancer tumors lack receptors for any of three bodily chemicals: estrogen, progesterone, and the HER2/neu gene. There are still effective treatments for it, such as chemotherapy, but doctors are not sure what stimulates this type of tumor to grow.

Women with a family history of breast cancer, specifically with the BRCA1 or BRCA2 breast gene mutation, are more at risk for developing Triple Negative Breast Cancer.

Related Questions

  • Christina Archambault Profile

    Any other BRCA1 positive girls or HER2 positive???

    Asked by anonymous

    Stage 2B Patient
    over 5 years 9 answers
    • View all 9 answers
    • sandra hayley Profile
      anonymous
      Learning About Breast Cancer

      Hi Christina, I've had cancer twice now, both times I had er, pr positive cancers. I went for genetic testing and found out I have the brca 2 gene. It is a little different from the brca1..but with both there is a higher risk of getting breast cancer again. Mine was 50-85% for getting breast...

      more

      Hi Christina, I've had cancer twice now, both times I had er, pr positive cancers. I went for genetic testing and found out I have the brca 2 gene. It is a little different from the brca1..but with both there is a higher risk of getting breast cancer again. Mine was 50-85% for getting breast cancer and the chance of getting ovarian was 30-40% . I've had cancer twice by the age of 40 and my mom passed away at 40. It is hard but try to stay positive. I've since had a laparoscopic hysterectomy(ovaries and tubes) taken out as a precaution to not getting this horrible disease again. Good luck, keep the faith.

      Comment
    • celien thorne Profile
      anonymous
      Patient

      I'm Her2 positive plus ER positive but tested negative for the gene ... Unfortunately we all face the threat of a reacurrence no matter what test we take or type of Breast Cancer we have ...stay active and fight this w all u can , live your life !

      Comment
  • Mary Foti Profile

    My mother's breast cancer recurred and is now stage 4. We are both positive for the BRCA2 mutation. I also had breast cancer in 2010. Does my mother's cancer recurrence mean my cancer will come back, too? We were both stage 1 when we were diagnosed.

    Asked by anonymous

    Survivor since 2010
    almost 6 years 4 answers
    • View all 4 answers
    • Thumb avatar default
      anonymous
      Learning About Breast Cancer

      That is very unfortunate news and I am sorry to hear it. I don't think it means that your cancer will return but I think it might be an idea to talk to your doctor about the options to help reduce the chance of it reoccurring. It might be an idea to consider a bi lateral mastectomy if you...

      more

      That is very unfortunate news and I am sorry to hear it. I don't think it means that your cancer will return but I think it might be an idea to talk to your doctor about the options to help reduce the chance of it reoccurring. It might be an idea to consider a bi lateral mastectomy if you haven't already. I have stage 2 IDC and don't have the gene but still chose to have a bilateral for my own peace of mind.

      Comment
    • Trish Watt Profile
      anonymous
      Learning About Breast Cancer

      Mary, Sorry to hear of the reoccurrence. I never had the test for BRCA2 but I went through 5 years of watching and waiting. The mental roller coaster I was on was more stressful than deciding and having a bi lateral mastectomy. Making that decision literally and physically lifted a big weight off...

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      Mary, Sorry to hear of the reoccurrence. I never had the test for BRCA2 but I went through 5 years of watching and waiting. The mental roller coaster I was on was more stressful than deciding and having a bi lateral mastectomy. Making that decision literally and physically lifted a big weight off of my shoulders. I had Stage I triple negative breast cancer which is a very aggressive type. Having the mastectomy was the best decision I ever made and I don't regret it at all. I'm sure you are younger than I was when diagnosed but who wants that hanging over your head. When you make the decision, and it has to be yours, you'll know it was the light one. Blessing and prayers for your family.

      Comment
  • Ashley Reynolds Profile

    Anyone here have the BRCA2 gene?

    Asked by anonymous

    Learning About Breast Cancer
    almost 6 years 2 answers
    • Thumb avatar default
      anonymous
      Learning About Breast Cancer

      I was first diagnosed with breast cancer in 1993 and it was DCIS on the left. I had a lumpectomy and radiation. Last February 2011 they found something on my mammo so I had a biopsy done which turned out to be a new cancer on the left side of DCIS again. They tested me and I am positive for...

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      I was first diagnosed with breast cancer in 1993 and it was DCIS on the left. I had a lumpectomy and radiation. Last February 2011 they found something on my mammo so I had a biopsy done which turned out to be a new cancer on the left side of DCIS again. They tested me and I am positive for BRCA2. My sister died from breast cancer and her granddaughter (age 27) was diagnosed with stage 2 cancer and she had BRCA2 as well. After having a bilateral mastectomy this time around, they also discovered I had breast cancer in the right breast which was ICLS. They are encouraging me to have my ovaries removed soon as the gene increases my chances for getting ovarian cancer. Rely on your doctors and other experts as your emotions can get out of control when you start listening to a lot of other people.

      4 comments
    • Evelyn Heilbrunn Profile
      anonymous
      Survivor since 2012

      Yes, I have the BRCA2 gene mutation. I first had breast cancer in 2000, at age 44. It was Stage 1B, no node involvement, DCIS with slight ductal invasion. I had a mastectomy and radiation. I was diagnosed in October 2011 with cancer in my remaining breast. It's not a recurrence but a new...

      more

      Yes, I have the BRCA2 gene mutation. I first had breast cancer in 2000, at age 44. It was Stage 1B, no node involvement, DCIS with slight ductal invasion. I had a mastectomy and radiation. I was diagnosed in October 2011 with cancer in my remaining breast. It's not a recurrence but a new cancer. Stage 2A, invasive ductal, with no node involvement but more aggressive and a larger tumor this time around. Given these facts, I was tested shortly after my second diagnosis in October 2011.

      Do you have more specific questions? I can tell you that your siblings and children, male and female, have a 50:50 chance of having the mutation. My one sibling, a sister in her early 50's, has tested positive. If inherited, there are increased risks for breast and other forms of cancer in both males and females, more so for females. First piece of advice: do not go on the internet and start searching. Rely on your doctors, geneticists, and other experts in the field. I'll be happy to answer any other questions or concerns you may have.

      Comment
  • Kay Roberts Profile

    Im 46 dx breast cancer HER2. Therapy starts this week. Im so nervous Worried about side effects. Do you remember your very FIRST treatment, What should I expect??? Has anyone found a solution to nausea???

    Asked by anonymous

    Stage 3A Patient
    over 5 years 7 answers
    • View all 7 answers
    • Jennifer Jones Profile
      anonymous
      Patient

      If you get a bad headache taking Zofran let your Dr. Know. I was allergic to it and had to go on another nausea medicine. Good luck!

      Comment
    • Thumb avatar default
      anonymous
      Learning About Breast Cancer

      I finished 6 treatments of tc a week ago. I was given zofran before each treatment was started, then I took one zofran that night and then 3 x a day for the next three days. Fortunately, I never had nausea. I was told if the zofran did not work I could take compazine. I was really worried about...

      more

      I finished 6 treatments of tc a week ago. I was given zofran before each treatment was started, then I took one zofran that night and then 3 x a day for the next three days. Fortunately, I never had nausea. I was told if the zofran did not work I could take compazine. I was really worried about side effects but just took and am taking one day (or hour) at a time. I wish you the best.

      Comment

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