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Types & Stages

 
Types & Stages

Chapter: 5 - Types & Stages

Subchapter: 6 - Triple Negative Breast Cancer

In Subchapter 3.1, “Growth of Cancer”, we discussed the role of receptors in cancer cells. Doctors seek to determine what causes certain types of cancer to progress by identifying its “receptors”. These receptors function like mouths: when open, the cancer cells feed and rapidly grow.

Triple Negative Breast Cancer tumors lack receptors for any of three bodily chemicals: estrogen, progesterone, and the HER2/neu gene. There are still effective treatments for it, such as chemotherapy, but doctors are not sure what stimulates this type of tumor to grow.

Women with a family history of breast cancer, specifically with the BRCA1 or BRCA2 breast gene mutation, are more at risk for developing Triple Negative Breast Cancer.

Related Questions

  • Mary Foti Profile

    My mother's breast cancer recurred and is now stage 4. We are both positive for the BRCA2 mutation. I also had breast cancer in 2010. Does my mother's cancer recurrence mean my cancer will come back, too? We were both stage 1 when we were diagnosed.

    Asked by anonymous

    Survivor since 2010
    over 6 years 4 answers
    • View all 4 answers
    • Thumb avatar default
      anonymous
      Learning About Breast Cancer

      That is very unfortunate news and I am sorry to hear it. I don't think it means that your cancer will return but I think it might be an idea to talk to your doctor about the options to help reduce the chance of it reoccurring. It might be an idea to consider a bi lateral mastectomy if you...

      more

      That is very unfortunate news and I am sorry to hear it. I don't think it means that your cancer will return but I think it might be an idea to talk to your doctor about the options to help reduce the chance of it reoccurring. It might be an idea to consider a bi lateral mastectomy if you haven't already. I have stage 2 IDC and don't have the gene but still chose to have a bilateral for my own peace of mind.

      Comment
    • Trish Watt Profile
      anonymous
      Learning About Breast Cancer

      Mary, Sorry to hear of the reoccurrence. I never had the test for BRCA2 but I went through 5 years of watching and waiting. The mental roller coaster I was on was more stressful than deciding and having a bi lateral mastectomy. Making that decision literally and physically lifted a big weight off...

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      Mary, Sorry to hear of the reoccurrence. I never had the test for BRCA2 but I went through 5 years of watching and waiting. The mental roller coaster I was on was more stressful than deciding and having a bi lateral mastectomy. Making that decision literally and physically lifted a big weight off of my shoulders. I had Stage I triple negative breast cancer which is a very aggressive type. Having the mastectomy was the best decision I ever made and I don't regret it at all. I'm sure you are younger than I was when diagnosed but who wants that hanging over your head. When you make the decision, and it has to be yours, you'll know it was the light one. Blessing and prayers for your family.

      Comment
  • Ashley Reynolds Profile

    Anyone here have the BRCA2 gene?

    Asked by anonymous

    Learning About Breast Cancer
    over 6 years 2 answers
    • Thumb avatar default
      anonymous
      Learning About Breast Cancer

      I was first diagnosed with breast cancer in 1993 and it was DCIS on the left. I had a lumpectomy and radiation. Last February 2011 they found something on my mammo so I had a biopsy done which turned out to be a new cancer on the left side of DCIS again. They tested me and I am positive for...

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      I was first diagnosed with breast cancer in 1993 and it was DCIS on the left. I had a lumpectomy and radiation. Last February 2011 they found something on my mammo so I had a biopsy done which turned out to be a new cancer on the left side of DCIS again. They tested me and I am positive for BRCA2. My sister died from breast cancer and her granddaughter (age 27) was diagnosed with stage 2 cancer and she had BRCA2 as well. After having a bilateral mastectomy this time around, they also discovered I had breast cancer in the right breast which was ICLS. They are encouraging me to have my ovaries removed soon as the gene increases my chances for getting ovarian cancer. Rely on your doctors and other experts as your emotions can get out of control when you start listening to a lot of other people.

      4 comments
    • Evelyn Heilbrunn Profile
      anonymous
      Survivor since 2012

      Yes, I have the BRCA2 gene mutation. I first had breast cancer in 2000, at age 44. It was Stage 1B, no node involvement, DCIS with slight ductal invasion. I had a mastectomy and radiation. I was diagnosed in October 2011 with cancer in my remaining breast. It's not a recurrence but a new...

      more

      Yes, I have the BRCA2 gene mutation. I first had breast cancer in 2000, at age 44. It was Stage 1B, no node involvement, DCIS with slight ductal invasion. I had a mastectomy and radiation. I was diagnosed in October 2011 with cancer in my remaining breast. It's not a recurrence but a new cancer. Stage 2A, invasive ductal, with no node involvement but more aggressive and a larger tumor this time around. Given these facts, I was tested shortly after my second diagnosis in October 2011.

      Do you have more specific questions? I can tell you that your siblings and children, male and female, have a 50:50 chance of having the mutation. My one sibling, a sister in her early 50's, has tested positive. If inherited, there are increased risks for breast and other forms of cancer in both males and females, more so for females. First piece of advice: do not go on the internet and start searching. Rely on your doctors, geneticists, and other experts in the field. I'll be happy to answer any other questions or concerns you may have.

      Comment
  • sally fakih Profile

    Er- , pr- , HER2- is that bad?

    Asked by anonymous

    Learning About Breast Cancer
    about 6 years 3 answers
    • Christina Archambault Profile
      anonymous
      Stage 2B Patient

      Me too just finished chemo I start start radiation June 4th...... Call on Jesus all things are possible !! Good luck in your journey !!

      Comment
    • Patricia Stoop Profile
      anonymous
      Learning About Breast Cancer

      Me too exactly a year ago! Locally advanced to lymph and maybe in liver but I am doing awesome now !!! That HER -2 - its like adding fuel to a fire.We are very lucky they discovered Herceptin for the HER-2. It's a life saver !!!! I have to take it all year long every 3 weeks with all the other...

      more

      Me too exactly a year ago! Locally advanced to lymph and maybe in liver but I am doing awesome now !!! That HER -2 - its like adding fuel to a fire.We are very lucky they discovered Herceptin for the HER-2. It's a life saver !!!! I have to take it all year long every 3 weeks with all the other treatments. Chemo, rads and surgery. Get ready for the ride of your life. I wish you all the best in your treatment and will pray and meditate for you!

      Comment
  • Thumb avatar default

    What is the difference if BRCA1 or BRCA2 is identified as the mutation?

    Asked by anonymous

    Learning About Breast Cancer
    over 6 years Answer

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