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Types & Stages

 
Types & Stages

Chapter: 5 - Types & Stages

Subchapter: 6 - Triple Negative Breast Cancer

In Subchapter 3.1, “Growth of Cancer”, we discussed the role of receptors in cancer cells. Doctors seek to determine what causes certain types of cancer to progress by identifying its “receptors”. These receptors function like mouths: when open, the cancer cells feed and rapidly grow.

Triple Negative Breast Cancer tumors lack receptors for any of three bodily chemicals: estrogen, progesterone, and the HER2/neu gene. There are still effective treatments for it, such as chemotherapy, but doctors are not sure what stimulates this type of tumor to grow.

Women with a family history of breast cancer, specifically with the BRCA1 or BRCA2 breast gene mutation, are more at risk for developing Triple Negative Breast Cancer.

Related Questions

  • sharon ayers Profile

    Is chemo always necessary if you are HER2 positive?

    Asked by anonymous

    Learning About Breast Cancer
    over 7 years 10 answers
    • View all 10 answers
    • Isabel Souchet Profile
      anonymous
      Survivor since 2010

      I know you have to do herceptin, which i did for a year. I also had chemo as I had a very small tumor (0.7cm) that was invasive ductal carcinoma. It depends on the tumor, size and many other factors. Don't let being her2 scare you, my oncologist said herceptin is a miracle drug and being her 2...

      more

      I know you have to do herceptin, which i did for a year. I also had chemo as I had a very small tumor (0.7cm) that was invasive ductal carcinoma. It depends on the tumor, size and many other factors. Don't let being her2 scare you, my oncologist said herceptin is a miracle drug and being her 2 was not bad.

      2 comments
    • Betsy Chapin Profile
      anonymous
      Survivor since 2010

      I also had stage 1 cancer, HER2 positive. I had a lumpectomy, chemo and radiation(in that order). I am not sure if HER2 positive patients always are a candidate for chemo, but your doctor will advise you on the best treatment for your situation. I also was in a medical trial where I did not get...

      more

      I also had stage 1 cancer, HER2 positive. I had a lumpectomy, chemo and radiation(in that order). I am not sure if HER2 positive patients always are a candidate for chemo, but your doctor will advise you on the best treatment for your situation. I also was in a medical trial where I did not get herceptin, but was given an oral medicine, lapatnib instead.

      Comment
  • Christina Archambault Profile

    Any other BRCA1 positive girls or HER2 positive???

    Asked by anonymous

    Stage 2B Patient
    over 7 years 9 answers
    • View all 9 answers
    • sandra hayley Profile
      anonymous
      Learning About Breast Cancer

      Hi Christina, I've had cancer twice now, both times I had er, pr positive cancers. I went for genetic testing and found out I have the brca 2 gene. It is a little different from the brca1..but with both there is a higher risk of getting breast cancer again. Mine was 50-85% for getting breast...

      more

      Hi Christina, I've had cancer twice now, both times I had er, pr positive cancers. I went for genetic testing and found out I have the brca 2 gene. It is a little different from the brca1..but with both there is a higher risk of getting breast cancer again. Mine was 50-85% for getting breast cancer and the chance of getting ovarian was 30-40% . I've had cancer twice by the age of 40 and my mom passed away at 40. It is hard but try to stay positive. I've since had a laparoscopic hysterectomy(ovaries and tubes) taken out as a precaution to not getting this horrible disease again. Good luck, keep the faith.

      Comment
    • celien thorne Profile
      anonymous
      Patient

      I'm Her2 positive plus ER positive but tested negative for the gene ... Unfortunately we all face the threat of a reacurrence no matter what test we take or type of Breast Cancer we have ...stay active and fight this w all u can , live your life !

      Comment
  • Thumb avatar default

    What is the difference if BRCA1 or BRCA2 is identified as the mutation?

    Asked by anonymous

    Learning About Breast Cancer
    over 8 years Answer
  • Christina Archambault Profile

    Is anyone else positive BRCA1? I got my genetics results and it was positive! I'm feeling very discouraged.

    Asked by anonymous

    Stage 2B Patient
    almost 8 years 2 answers
    • Mary Foti Profile
      anonymous
      Survivor since 2010

      I am positive for BRCA2. It was hard news to hear - I completely understand. But think of it this way - if you have already been diagnosed with breast or ovarian cancer, you now know exactly why it happened. Most women never know what caused their cancer. Whether you have or haven't developed...

      more

      I am positive for BRCA2. It was hard news to hear - I completely understand. But think of it this way - if you have already been diagnosed with breast or ovarian cancer, you now know exactly why it happened. Most women never know what caused their cancer. Whether you have or haven't developed cancer at this point, you will face some hard choices ahead - BUT, you now have the gift of very empowering information that can help you and your doctor make potentially life-saving decisions regarding preventive surgery and/or surveillance options. And if you choose to share your genetic testing results, you are giving that gift of potentially life-saving information for your family members. 4 of my relatives have tested positive since my diagnosis and are all taking action to reduce their future risks. Had I not had the testing, they would not have known how high their risks were. Bless you during this difficult time - I know it is VERY hard!

      Comment
    • Thumb avatar default
      anonymous
      Learning About Breast Cancer

      I recently found out that I was BRCA positive. I was disappointed scared and cried for a week. I had a complete hysterectomy using the da Vinci robot four weeks ago. I feel great and I recommend the surgery. I still have a lot of decisions to make. I am considering taking tamoxifen. The...

      more

      I recently found out that I was BRCA positive. I was disappointed scared and cried for a week. I had a complete hysterectomy using the da Vinci robot four weeks ago. I feel great and I recommend the surgery. I still have a lot of decisions to make. I am considering taking tamoxifen. The bilateral vasectomy is still overwhelming.

      1 comment

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Breast cancer affects one out of every eight women in their lifetime.

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